diff --git a/rules-tests/DeadCode/Rector/Expression/RemoveDeadStmtRector/Fixture/skip_clone_has_clone.php.inc b/rules-tests/DeadCode/Rector/Expression/RemoveDeadStmtRector/Fixture/skip_clone_has_clone.php.inc
new file mode 100644
index 00000000000..2fe3ee83ed2
--- /dev/null
+++ b/rules-tests/DeadCode/Rector/Expression/RemoveDeadStmtRector/Fixture/skip_clone_has_clone.php.inc
@@ -0,0 +1,14 @@
+<?php
+
+namespace Rector\Tests\DeadCode\Rector\Expression\RemoveDeadStmtRector\Fixture;
+
+final class SkipCloneHasClone
+{
+    public function __clone()
+    {
+        throw new \RuntimeException('clone is not allowed');
+    }
+}
+
+$obj = new SkipCloneHasClone();
+clone $obj;
diff --git a/rules/DeadCode/NodeManipulator/LivingCodeManipulator.php b/rules/DeadCode/NodeManipulator/LivingCodeManipulator.php
index 2b1313799c3..1b24ab7638f 100644
--- a/rules/DeadCode/NodeManipulator/LivingCodeManipulator.php
+++ b/rules/DeadCode/NodeManipulator/LivingCodeManipulator.php
@@ -30,13 +30,16 @@
 use PhpParser\Node\Expr\UnaryPlus;
 use PhpParser\Node\Expr\Variable;
 use PhpParser\Node\Scalar;
+use PHPStan\Reflection\ReflectionProvider;
 use PHPStan\Type\ObjectType;
 use Rector\NodeTypeResolver\NodeTypeResolver;
+use Rector\ValueObject\MethodName;
 
 final readonly class LivingCodeManipulator
 {
     public function __construct(
-        private NodeTypeResolver $nodeTypeResolver
+        private NodeTypeResolver $nodeTypeResolver,
+        private ReflectionProvider $reflectionProvider
     ) {
     }
 
@@ -53,6 +56,10 @@ public function keepLivingCodeFromExpr(Node | int | string | null $expr): array
             return [];
         }
 
+        if ($expr instanceof Clone_ && $this->hasCloneMagicMethod($expr)) {
+            return [$expr];
+        }
+
         if ($this->isNestedExpr($expr)) {
             return $this->keepLivingCodeFromExpr($expr->expr);
         }
@@ -110,6 +117,23 @@ private function isNestedExpr(Expr $expr): bool
             $expr instanceof Clone_;
     }
 
+    private function hasCloneMagicMethod(Clone_ $clone): bool
+    {
+        $cloneObjectType = $this->nodeTypeResolver->getType($clone->expr);
+
+        foreach ($cloneObjectType->getObjectClassNames() as $className) {
+            if (! $this->reflectionProvider->hasClass($className)) {
+                continue;
+            }
+
+            if ($this->reflectionProvider->getClass($className)->hasNativeMethod(MethodName::CLONE)) {
+                return true;
+            }
+        }
+
+        return false;
+    }
+
     private function isBinaryOpWithoutChange(Expr $expr): bool
     {
         if (! $expr instanceof BinaryOp) {